PreveCeutical Reaches Milestone in Research Program for Development of Non-Addictive Analgesics
Vancouver, British Columbia: PreveCeutical Medical Inc. (the “Company” or “PreveCeutical”)(CSE: PREV, OTCQB: PRVCF, FSE: 18H), is pleased to announce that it has recently reached a significant milestone in its research program for the development of non-addictive analgesics (the “Research Program”) encompassing the design, synthesis and cell-based screening of lead peptide constructs intended for development as non-addictive painkilling medicines as a replacement for highly addictive analgesics, such as morphine.
PreveCeutical’s research team previously identified no less than five novel peptide constructs, which preferentially target the receptor subtype which is of interest to the Company and is purported to avoid addictive and tolerance-inducing side effects (see news release dated January 8, 2019).
PreveCeutical’s President and Chief Science Officer, Dr. Mak Jawadekar stated, “In light of the recent news regarding some judgements and fines as a result of the lawsuits against certain opioid manufacturers and distributors that marketed and proliferated dangerous painkillers, PreveCeutical’s successful advancement of the non-addictive analgesics/painkiller program provides great potential options for a safe and effective means to alleviate the current drug crisis situation.”
Furthermore, it was confirmed that this novel subset of peptides demonstrated potency, in a well-accepted functional dose response assay, that is on par with clinically available agents, such as morphine.
Through an iterative process encompassing in silico modelling, peptide library synthesis and screening in a cell-based functional assay, the Company has identified a panel of novel peptide constructs which selectively target the opioid receptor sub-type of interest and are highly potent and stable for extended periods in biological fluids.
PreveCeutical intends for the Research Program to progress into preclinical evaluations of the lead, highly potent and stable peptide candidates in a well-established model of pain and inflammation. Further, PreveCeutical expects that the results of these studies will be reported in due course.
Resignation of Director
PreveCeutical also announces the resignation of Matthew Coltura as a director and member of the audit committee of the board of directors of the Company, effective September 1, 2019. The Company wishes to thank Mr. Coltura for his contributions to the Company and wishes him all the best in his future endeavours.
PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.
PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for type 2 diabetes and obesity; a soluble gel drug delivery program; Nature Identical™peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).
On Behalf of the Board of Directors
“Stephen Van Deventer”
Chairman and CEO
For further information, please contact:
Director of Corporate Communications & Investor Relations
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